V20103

DATASHEET

Host: Mouse

Target Protein: IgA

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 3493

Purification: affinity purified by Protein A

Storage Buffer: 0.01M PBS(pH7.4)

Storage: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:

Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B-cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.

Size: 1mg

Concentration: Lot Dependent

Applications: ELISA(1:500-1000)
LFA(N/A)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.