V5704

DATASHEET

Host: Mouse

Target Protein: Alpha-synuclein

Clonality: Monoclonal

Isotype: IgG2a

Entrez Gene: 6622

Purification: affinity purified by Protein A

Storage Buffer: 0.01M PBS(pH7.4).

Storage: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].

Size: 1mg

Concentration: Lot Dependent

Applications: ELISA(1:500-1000)
LFA(N/A)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.