DATASHEET
Host:
Mouse
Target Protein:
MMP9
Clonality:
Monoclonal
Isotype:
IgG2b
Entrez Gene:
4318
Purification:
affinity purified by Protein A
Storage Buffer:
0.01M PBS (pH7.4).
Storage:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
bs-7059P is one synthetic peptide derived from human MMP-9.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008].