V9002

DATASHEET

Host: Mouse

Target Protein: Thyroglobulin

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 7038

Purification: affinity purified by Protein A

Storage Buffer: 0.01M PBS (pH7.4).

Storage: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:

Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Size: 1mg

Concentration: Lot Dependent

Applications: ELISA(1:500-1000)
LFA(N/A)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.