Target Protein: Adrenomedullin
Immunogen Range: 122-140/185
Entrez Gene: 133
Swiss Prot: P35318
Source: KLH conjugated synthetic peptide derived from human Adrenomedullin
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at 4°C for 12 months.
Background: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Cross Reactive Species: Rat
Predicted Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.