bs-0042R-FITC [Conjugated Primary Antibody]
ChAT Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ChAT

Immunogen Range: 101-200/748


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1103

Swiss Prot: P28329

Source: KLH conjugated synthetic peptide derived from human ChAT

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 82


Cross Reactive Species: Human
Mouse
Rat
Dog

Predicted Cross Reactive Species: Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang Y, Zheng S, Geng Y, Xue J, Wang Z, et al. (2015) MicroRNA Profiling of Atrial Fibrillation in Canines: MiR-206 Modulates Intrinsic Cardiac Autonomic Nerve Remodeling by Regulating SOD1. PLoS ONE 10(3): e0122674. Read more>>
  • Wieck, Minna M., et al. "Human and murine tissue-engineered colon exhibit diverse neuronal subtypes and can be populated by enteric nervous system progenitor cells when donor colon is aganglionic." Tissue Engineering A (2015).Read more>>
  • Zhang, Xiuli, et al. "Catalpol improves cholinergic function and reduces inflammatory cytokines in the senescent mice induced by D-galactose."Food and chemical toxicology 58 (2013): 50-55.Read more>>
  • Wieck et al. Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. (2016) Tissue.Eng.Part.A. 22:53-64Read more>>
  • Wang,et al.Stimulation of Epicardial Sympathetic Nerves at Different Sites Induces Cardiac Electrical Instability to Various Degrees.(2018) Scientific Reports. 8:994.Read more>>
  • Jiasuoer Xiaokereti. et al. Enhanced atrial internal-external neural remodeling facilitates atrial fibrillation in the chronic obstructive sleep apnea model. Plos One. 2021 Feb;16(2):e0247308Read more>>
  • Daisuke Koga. et al. Applications of Scanning Electron Microscopy Using Secondary and Backscattered Electron Signals in Neural Structure. Front Neuroanat. 2021; 15: 759804Read more>>
  • Wei Lu. et al. Effects of targeted muscle reinnervation on spinal cord motor neurons in rats following tibial nerve transection. Neural Regen Res. 2022 Jan;17(8):1827Read more>>
  • Xiaokereti, Jiasuoer. et al. Renal denervation alleviates chronic obstructive sleep apnea-induced atrial fibrillation via inhibition of atrial fibrosis and sympathetic hyperactivity. SLEEP BREATH. 2023 Feb;:1-14Read more>>
VALIDATION IMAGES