bs-0061R-A488 [Conjugated Primary Antibody]
beta Actin Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: beta-Actin

Immunogen Range: 1-200/375


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 60

Swiss Prot: P60709

Source: MAP conjugated synthetic peptide derived from human beta Actin

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Background:

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 499nm/519nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 42


Cross Reactive Species: Human
Mouse
Rat
Bovine
Dog
Pig
Sheep
Rabbit
Goat
Others
All

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Han, Jianfeng, et al. "Cationic Bovine Serum Albumin Based Self‐Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer." Small 10.3 (2014): 524-535.Read more>>
  • Teng, I., et al. "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." Biomaterials (2013).Read more>>
  • Xiang, Bai, et al. "PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer." Biomaterials (2013).Read more>>
  • Li, Xiaoxia, et al. "AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells." Arteriosclerosis, thrombosis, and vascular biology 28.10 (2008): 1789-1795.Read more>>
  • Ma, Yanqin, et al. "Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta." Archives of toxicology 86.6 (2012): 849-856.Read more>>
  • Zeng, Xiaoyun, et al. "A Newly Synthesized Sinapic Acid Derivative Inhibits Endothelial Activation In Vitro and In Vivo." Molecular Pharmacology (2013).Read more>>
  • Wang, Ye-Jun, et al. "Two oral HBx vaccines delivered by live attenuated< i> Salmonella</i>: Both eliciting effective anti-tumor immunity." Cancer letters 263.1 (2008): 67-76.Read more>>
  • Fu, Chenglai, et al. "Cholesterol increases adhesion of monocytes to endothelium by moving adhesion molecules out of caveolae." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1801.7 (2010): 702-710.Read more>>
  • Yin, Di, et al. "Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo." Nanotechnology 24.10 (2013): 105102.Read more>>
  • Yin, Di, et al. "Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo." Nanotechnology 24.10 (2013): 105102.Read more>>
  • Wang, Wei, et al. "Cynoglossus semilaevis ISG15: A Secreted Cytokine-Like Protein That Stimulates Antiviral Immune Response in a LRGG Motif-Dependent Manner." PLOS ONE 7.9 (2012): e44884.Read more>>
  • Gao, Jin-Hang, et al. "Celecoxib Ameliorates Portal Hypertension of the Cirrhotic Rats through the Dual Inhibitory Effects on the Intrahepatic Fibrosis and Angiogenesis." PLOS ONE 8.7 (2013): e69309.Read more>>
  • Hou, Cong-Cong, and Wan-Xi Yang. "Acroframosome-Dependent KIFC1 Facilitates Acrosome Formation during Spermatogenesis in the Caridean Shrimp Exopalaemon modestus."?PLOS ONE?8.9 (2013): e76065.Read more>>
  • Shi, Ran-ran, et al. "The immunogenicity of a novel cytotoxic T lymphocyte epitope from tumor antigen PL2L60 could be enhanced by 4-chlorophenylalanine substitution at position 1."?Cancer Immunology, Immunotherapy?(2013): 1-10.Read more>>
  • Guo, Hong-Feng, et al. "Piezoelectric PU/PVDF electrospun scaffolds for wound healing applications." Colloids and Surfaces B: Biointerfaces (2012).Read more>>
  • Li, Bing-Hua, et al. "Polypeptide from Chlamys farreri inhibits UVB-induced HaCaT cells apoptosis via inhibition CD95 pathway and reactive oxygen species." Free radical research 41.11 (2007): 1224-1232.Read more>>
  • Chen, Cheng, et al. "The galectin-3-binding protein of< i> Cynoglossus semilaevis</i> is a secreted protein of the innate immune system that binds a wide range of bacteria and is involved in host phagocytosis." Developmental & Comparative Immunology (2012).Read more>>
  • Qiu, Reng, et al. "Macrophage migration inhibitory factor of< i> Sciaenops ocellatus</i> regulates immune cell trafficking and is involved in pathogen-induced immune response." Developmental & Comparative Immunology (2013).Read more>>
  • Zhang, Jian, Ling Chen, and Li Sun. "SmLMWPTP, a teleost low molecular weight protein tyrosine phosphatase, inhibits the immune response of peripheral blood leukocytes in a manner that depends on the conserved P-loop." Developmental & Comparative Immunology (2013).Read more>>
  • Li, Mo-fei, et al. "First characterization of a teleost Epstein-Barr virus-induced gene 3 (EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes." Developmental & Comparative Immunology (2013).Read more>>
  • Chen, Cheng, et al. "The galectin-3-binding protein of< i> Cynoglossus semilaevis</i> is a secreted protein of the innate immune system that binds a wide range of bacteria and is involved in host phagocytosis." Developmental & Comparative Immunology (2012).Read more>>
  • Liu, Ping, et al. "Effects of pubertal fenvalerate exposure on testosterone and estradiol synthesis and the expression of androgen and estrogen receptors in the developing brain." Toxicology Letters 201.2 (2011): 181-189.Read more>>
  • Ye, R., et al. "Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia." Neuroscience 178 (2011): 169-180.Read more>>
  • Liu, Donghui, et al. "Nonenzymatic glycation of high?\density lipoprotein impairs its anti?\inflammatory effects in innate immunity."iabetes/Metabolism Research and Reviews 28.2 (2012): 186-195..3Read more>>
  • Sun, Yuan, et al. "Carbon disulfide exposure at peri-implantation disrupts embryo implantation by decreasing integrin ??< sub> 3</sub> expression in the uterine tissue of pregnant mice."Chemico-biological interactions?(2013).xRead more>>
  • Yu, Lan-ping, et al. "Characterization of a c-type lysozyme of Scophthalmus maximus: expression, activity, and antibacterial effect." Fish & Shellfish Immunology (2012).Read more>>
  • Zhong, Zhiwei, et al. "miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer." Journal of cancer research and clinical oncology 138.10 (2012): 1781-1788.Read more>>
  • Ye, Ruidong, et al. "Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats." Neurochemistry international 58.3 (2011): 391-398.Read more>>
  • Han, Xiaohua, et al. "Antioxidant action of 7, 8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity." Neurochemistry International (2013).Read more>>
  • Feng, Ming, et al. "Ulinastatin Attenuates Experimental Autoimmune Encephalomyelitis by Enhancing Anti-inflammatory Responses." Neurochemistry international (2013).Read more>>
  • Zhong, Zhiwei, et al. "MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells." Tumor Biology (2013): 1-7.Read more>>
  • He, Siyi, et al. "miR-138 protects cardiomyocytes from hypoxia-induced apoptosis via MLK3/JNK/c-jun pathway." Biochemical and biophysical research communications (2013).Read more>>
  • Pan, Lin, et al. "Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells." Molecular and cellular biochemistry 355.1-2 (2011): 257-263.Read more>>
  • Deng, Xiao Li, et al. "Comparative study on circulating endothelial progenitor cells in systemic lupus erythematosus patients at active stage." Rheumatology international 30.11 (2010): 1429-1436.Read more>>
  • Gao, Wei, et al. "Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma." Medical Oncology 30.2 (2013): 1-8.Read more>>
  • Zhang, Zhan, et al. "Differential expression of beta-catenin and dickkopf-1 in the third trimester placentas from normal and preeclamptic pregnancies: a comparative study." Reproductive Biology and Endocrinology 11.1 (2013): 17.Read more>>
  • Ruan Lin, et al. "Tetrandrine Attenuated Cerebral Ischemia/Reperfusion Injury and Induced Differential Proteomic Changes in a MCAO Mice Model Using 2-D DIGE." Neurochemical Research (2013). 1-9.Read more>>
  • Tao, Liu, et al. "In vitro study on human cytomegalovirus affecting early pregnancy villous EVT??s invasion function."Virology Journal 8.1 (2011): 1-8.DRead more>>
  • Nie, Lihong, et al. "The anti-apoptotic effect of hydrogen sulfide attenuates injuries to the medullary respiratory centers of neonatal rats subjected to in utero cigarette smoke exposure." Respiratory physiology & neurobiology (2013).Read more>>
  • Chen, Cui-Ying, et al. "Characterization of cytotoxicity-related gene expression in response to virulent Marek??s disease virus infection in the bursa of Fabricius."Research in veterinary science (2012).qRead more>>
  • Wang, Peng, et al. "Recombinant adenovirus expressing ICP47 gene suppresses the ability of dendritic cells by restricting specific T cell responses." Cellular Immunology (2013).Read more>>
  • GAO, DAN, et al. "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." Nephrology 16.8 (2011): 736-742.Read more>>
  • Wang, Chunqiang, Wei Ma, and Yuhong Su. "NF-??B Pathway Contributes to Cadmium-Induced Apoptosis of Porcine Granulosa Cells."Biological trace element research (2013): 1-8.cRead more>>
  • Zhao, Yu, and Shijun Wang. "Neural Stem Cell Transplantation Inhibits Apoptosis through Activation of MAPK/ERK Signaling Pathway in Cerebral Ischemia/Reperfusion Rats." International Journal of Clinical and Experimental Neurology 1.1 (2013): 5-11.Read more>>
  • Zhou, Jing, et al. "Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats."?Experimental & Clinical Cardiology?18.2 (2013): e95.Read more>>
  • Zhang, Xiao-ling, et al. "Vascular endothelial growth factor up-regulates the expression of intracellular adhesion molecule-1 in retinal endothelial cells via reactive oxygen species, but not nitric oxide." Chinese Medical Journal (English Edition) 122.3 (2009): 338.Read more>>
  • Wang, Gui-Jun, et al. "Expression of tissue factor pathway inhibitor-2 in gastric stromal tumor and its clinical significance." Experimental and Therapeutic Medicine.Read more>>
  • Xu, R., et al. "Secretoneurin Induces Airway Mucus Hypersecretion by Enhancing the Binding of EGF to NRP1." Cellular Physiology and Biochemistry 33.2 (2014): 446-456.Read more>>
  • Zeng, Q. J., et al. "Decorin-induced proliferation of avian myoblasts involves the myostatin/Smad signaling pathway." Poultry Science 93.1 (2014): 138-146.Read more>>
  • Liu, Qun, et al. "6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α." Molecular cancer 12.1 (2013): 135.Read more>>
VALIDATION IMAGES