bs-0064R-Cy5 [Conjugated Primary Antibody]
Neurokinin 1 Receptor Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Neurokinin 1 Receptor

Immunogen Range: 2-50/407


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6869

Swiss Prot: P25103

Source: KLH conjugated synthetic peptide derived from human Neurokinin 1 Receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 45


Cross Reactive Species: Human
Rat
Others

Predicted Cross Reactive Species: Mouse
Dog
Cow
Pig
Horse
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • 任绪莹, et al. "小半夏汤对水貂呕吐模型作用机制的研究." Acta Neuropharmacologica 1.3 (2011).Read more>>
  • 杨玉玲, et al. "姜辣素辅助昂丹司琼对顺铂所致大鼠异嗜行为的抑制作用." 世界华人消化杂志 19.10 (2011): 1034-1039.Read more>>
  • Zhang et al. Effects of Neuropeptide Substance P on Proliferation and β-Cell Differentiation of Adult Pancreatic Ductal Cells. (2018) Front.Neurosci. 12:807Read more>>
  • Tian L et al. Gingerol inhibits cisplatin-induced acute and delayed emesis in rats and minks by regulating the central and peripheral 5-HT, SP, and DA systems. J Nat Med. 2019 Nov 25. Read more>>
  • Jinbo Li. et al. Low dose shikonin and anthracyclines coloaded liposomes induce robust immunogenetic cell death for synergistic chemo-immunotherapy. J Control Release. 2021 Jul;335:306Read more>>
  • Jimei Zhang. et al. Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor. PHARM BIOL. 2023;61(1):449-458Read more>>
VALIDATION IMAGES