bs-0065R-A594 [Conjugated Primary Antibody]
Substance P Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Substance P

Immunogen Range: 58-68/129


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6863

Swiss Prot: P20366

Source: KLH conjugated synthetic peptide derived from human SP

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Background:

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Conjugation: ALEXA FLUOR® 594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 1_13_


Cross Reactive Species: Mouse
Rat
Others

Predicted Cross Reactive Species: Human
Cow
Sheep
Pig
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Tu, Guihua, et al. "P2X< sub> 7</sub> inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." Brain research bulletin (2013).Read more>>
  • Liu, Jun, et al. "Sensory–sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." Purinergic Signalling (2013): 1-17.Read more>>
  • Liu, Zhi-ming, et al. "Mutual Effect between Neuropeptides and Inflammatory Cytokines in Neurogenic SMSCs of Human Temporomandibular Joint." J Huazhong Univ Sci Technol [Med Sci] 34.4 (2014): 602-607.Read more>>
  • Daschil, Nina, et al. "L-Type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model." Neurobiology of Aging (2015).Read more>>
  • Yu, Xi-Jiao, et al. "Expression of substance P in rat periodontal alveolar bone after denervation." International Journal of Clinical and Experimental Pathology 9.2 (2016): 1384-1391.Read more>>
  • ileum&area postremaRead more>>
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  • Jungen C et al. Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation. Am J Physiol Heart Circ Physiol. 2019 Oct 18.Read more>>
  • in Feng. et al. Li-ESWT treatment reduces inflammation, oxidative stress, and pain via the PI3K/AKT/FOXO1 pathway in autoimmune prostatitis rat models. 2021 May 07Read more>>
  • Shengyan Xi. et al. The Ciji-Huaai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H22 Hepatocellular Carcinoma. Front Pharmacol. 2021; 12: 715824Read more>>
  • Liu Dan. et al. RSV Promotes Epithelial Neuroendocrine Phenotype Differentiation through NODAL Signaling Pathway. Biomed Res Int. 2021;2021:9956078Read more>>
VALIDATION IMAGES