bs-0067R-A350 [Conjugated Primary Antibody]
NGF beta Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: NGF beta

Immunogen Range: 151-220/241


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4803

Swiss Prot: P01138

Source: KLH conjugated synthetic peptide derived from human NGF beta

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 13/32


Cross Reactive Species: Human
Mouse
Rat
Dog

Predicted Cross Reactive Species: Cow
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Jianhai, et al. "Choline supplementation alleviates fluoride-induced testicular toxicity by restoring the NGF and MEK expression in mice."Toxicology and Applied Pharmacology 310 (2016): 205-214.Read more>>
  • Li, Xiaoming, et al. "Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma." Acta oto-laryngologica 132.3 (2012): 314-324.Read more>>
  • Lu, Yanmei, et al. "Effect of Low-level Vagus Nerve Stimulation on Cardiac Remodeling in a Rapid Atrial Pacing–induced Canine Model of Atrial Fibrillation." Journal of cardiovascular pharmacology 67.3 (2016): 218-224.Read more>>
  • Li, Hui, et al. "Therapeutic potential of in utero mesenchymal stem cell (MSCs) transplantation in rat foetuses with spina bifida aperta." Journal of cellular and molecular medicine 16.7 (2012): 1606-1617.Read more>>
  • Shu et al. Connexin 43 is involved in the sympathetic atrial fibrillation in canine and canine atrial myocytes. (2017) Anatol.J.Cardiol. 18:3-9Read more>>
  • Fu XM et al. The Combination of Adipose-derived Schwann-like Cells and Acellular Nerve Allografts PromotesSciatic Nerve Regeneration and Repair through the JAK2/STAT3 Signaling Pathway in Rats. Neuroscience. 2019 Nov 1;422:134-145. Read more>>
  • Chengjie Wu. et al. Icariin promotes the repair of PC12 cells by inhibiting endoplasmic reticulum stress. Bmc Complem Altern M. 2021 Dec;21(1):1-8Read more>>
  • Zhou, Zhen. et al. Metabolism regulator adiponectin prevents cardiac remodeling and ventricular arrhythmias via sympathetic modulation in a myocardial infarction model. BASIC RES CARDIOL. 2022 Dec;117(1):1-17Read more>>