bs-0076M [Primary Antibody]
beta Amyloid 1-42 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: beta Amyloid 1-42

Immunogen Range: 35-42/42


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 320

Swiss Prot: Q02410

Source: KLH conjugated synthetic peptide derived from human beta-Amyloid 1-42

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 4.4


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Dog
Cow
Pig
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hu, Tao, et al. "Antibody modified-silver nanoparticles for colorimetric immuno sensing of Aβ (1-40/1-42) based on the interaction between β-amyloid and Cu 2+." Sensors and Actuators B: Chemical (2016).Read more>>
  • Meng L et al. Anthocyanins Extracted from Aronia melanocarpa Protect SH-SY5Y Cells against Amyloid-beta (1-42)-Induced Apoptosis by Regulating Ca2+ Homeostasis and Inhibiting Mitochondrial Dysfunction.(2018) J Agric Food Chem. Nov 28.Read more>>
  • Xue Gao. et al. Quantitative imaging of amyloid beta peptide (A) in Alzheimers brain tissue by laser ablation ICP-MS using gold nanoparticles as labels. Anal Chim Acta. 2021 Mar;1148:238197Read more>>
  • Yu-Shi Gong. et al. Effects of alcohol intake on cognitive function and -amyloid protein in APP/PS1 transgenic mice. Food Chem Toxicol. 2021 May;151:112105Read more>>
  • Dongmiao Qin. et al. Design of a Dual-Wavelength Ratiometric Electrochemiluminescence Immunosensor for Sensitive Detection of Amyloid- Protein in Human Serum. Acs Sustain Chem Eng. 2021;9(22):7541C7549Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse hippocampus labeled with Anti-B-Amyloid 1-42(CT) Polyclonal Antibody, Unconjugated (bs-0076M), followed by conjugation to the secondary antibody and DAB staining