bs-0088R-Cy5 [Conjugated Primary Antibody]
Secretin Polyclonal Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Secretin

Immunogen Range: 28-54/121

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6343

Source: KLH conjugated synthetic peptide derived from human Secretin

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage: Store at 4°C for 12 months.

Background: Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 3

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang et al. The knockout of secretin in cerebellar Purkinje cells impairs mouse motor coordination and motor learning. (2014) Neuropsychopharmacolog. 39:1460-8Read more>>
  • Lixian Chen. et al. Inhibition of secretin/secretin receptor axis ameliorates non\alcoholic fatty liver disease phenotypes. 2021 Apr 3Read more>>