bs-0089R [Primary Antibody]
Secretin receptor Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Secretin receptor

Immunogen Range: 188-280/440


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6344

Swiss Prot: P47872

Source: KLH conjugated synthetic peptide derived from human of human Secretin receptor

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(IHC-P)(1:100-500)
IF(IHC-F)(1:100-500)
IF(ICC)(1:100-500)

Predicted Molecular Weight: 46


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Dog
Cow
Sheep
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhou T et al. Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.Lab Invest. 2018 Nov;98(11):1449-1464Read more>>
  • Peder Berg. et al. Impaired Renal HCO3- Excretion in Cystic Fibrosis. J Am Soc Nephrol. 2020 Aug;31(8):1711-1727Read more>>
  • Lixian Chen. et al. Inhibition of secretin/secretin receptor axis ameliorates non\alcoholic fatty liver disease phenotypes. 2021 Apr 3Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse thyroid labeled with Anti-Secretin receptor Polyclonal Antibody, Unconjugated (bs-0089R) at 1:200 followed by conjugation to the secondary antibody and DAB staining