bs-0092R-A350 [Conjugated Primary Antibody]
Caspase-10 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
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Host: Rabbit

Target Protein: Caspase-10

Immunogen Range: 431-521/521

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 843

Swiss Prot: Q92851

Source: KLH conjugated synthetic peptide derived from human Caspase-10

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage: Store at 4°C for 12 months.

Background:

Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 343nm/442nm

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 59

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.