Host: Rabbit
Target Protein: CRP
Immunogen Range: 125-224/224
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1401
Swiss Prot: P02741
Source: KLH conjugated synthetic peptide derived from human CRP
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at 4°C for 12 months.
Background: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Conjugation: Cy3
Excitation/ Emission: 512,550nm/570,615nm
Size: 100ul
Concentration: 1ug/ul
Applications:
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Cross Reactive Species:
Human
Mouse
Predicted Cross Reactive Species:
Rat
Dog
Pig
Rabbit
For research use only. Not intended for diagnostic or therapeutic use.
- Guo, Fang, et al. "Fibrinogen, fibrin, and FDP induce C-reactive protein generation in rat vascular smooth muscle cells: Pro-inflammatory effect on atherosclerosis." Biochemical and biophysical research communications 390.3 (2009): 942-946.Read more>>
- Ding, Lin, et al. "Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism." Journal of Functional Foods 32 (2017): 90-97.Read more>>
- Zhang L et al. Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice. Food & Function. 2019 Read more>>
- Rong Z et al. A C-reactive protein immunosensor based on platinum nanowire/titania nanotube composite sensitized electrochemiluminescence. Talanta, 2019.205, 120135. Read more>>
- Liu X et al. Polydopamine-based molecular imprinted optic microfiber sensor enhanced by template-mediated molecular rearrangement for ultra-sensitive C-reactive protein detection. Chemical Engineering Journal. 2020, May 387: 124074.Read more>>
- Jin Z et al. Geniposide alleviates atherosclerosis by regulating macrophage polarization via the FOS/MAPK signaling pathway. Biomed Pharmacother. 2020 May;125:110015. Read more>>