bs-0164R-A555 [Conjugated Primary Antibody]
BACE1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]

Host: Rabbit

Target Protein: BACE1

Immunogen Range: 401-501/501

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23621

Swiss Prot: P56817

Source: KLH conjugated synthetic peptide derived from human BACE1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.


Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Conjugation: ALEXA FLUOR® 555

Excitation/ Emission: 555nm/580nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 51

Cross Reactive Species: Human

Predicted Cross Reactive Species: Dog
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

  • Tian, Yue, et al. "Minocycline Alleviates Sevoflurane-Induced Cognitive Impairment in Aged Rats." Cellular and Molecular Neurobiology (2015): 1-10.Read more>>
  • Hong, Yan, et al. "Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus." Neurochemical Research: 1-8.Read more>>
  • Yan, Wei, et al. "NO2 inhalation promotes Alzheimer’s disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication." Scientific Reports 6 (2016): 22429.Read more>>
  • Jiao, Yanan, et al. "Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer's disease." Neuropharmacology (2016).Read more>>
  • Ku, Tingting, et al. "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM 2.5 aspiration." Particle and Fibre Toxicology 14.1 (2017): 34.Read more>>
  • Yuan C et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.(2019) Biochim Biophys Acta Mol Basis Dis.Jan;1865(1):161-180.Read more>>
  • Lei Jiang. et al. Advanced glycation end products induce A142 deposition and cognitive decline through H19/miR-15b/BACE1 axis in diabetic encephalopathy. BRAIN RES BULL. 2022 Oct;188:187Read more>>