bs-0211R-A350 [Conjugated Primary Antibody]
SHANK 1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
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Host: Rabbit

Target Protein: SHANK 1

Immunogen Range: 101-200/2161


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 50944

Swiss Prot: Q9Y566

Source: KLH conjugated synthetic peptide derived from human Shank1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 225


Predicted Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Chi, et al. "The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer’s disease." Journal of Controlled Release (2014).Read more>>