bs-0213R-HRP [Conjugated Primary Antibody]
HCV-NS4a Polyclonal Antibody, HRP Conjugated
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Host: Rabbit

Target Protein: HCV-NS4a

Immunogen Range: 1658-1711/3010


Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from HCV-NS4a

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Hepatitis C virus (HCV) is an enveloped, positive-strand RNA virus classified within the genus Hepacivirus in the family Flaviviridae. The nonsegmented HCV genome is 9.6-kb and encodes a long polyprotein that is cleaved by cellular and viral proteases into at least 10 distinct products. The N-terminal region of this polyprotein encodes the viral structural proteins: core and two envelope glycoproteins, E1 and E2. The remainder of the polyprotein encodes nonstructural (NS) proteins: p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. NS4A is the smallest NS protein. It encodes an N-terminal hydrophobic alpha-helix that anchors NS3-4A to cellular membranes, a middle cofactor peptide that forms a beta-strand and contributes to proper folding of the NS3 serine protease domain, and a C-terminal acidic region that forms an alpha-helix at low pH.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)

Predicted Molecular Weight: 5


Cross Reactive Species: Virus
(HCV)

For research use only. Not intended for diagnostic or therapeutic use.