bs-0215R-Cy3 [Conjugated Primary Antibody]
CD95 Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD95

Immunogen Range: 20-70/327

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 14102

Swiss Prot: P25446

Source: KLH conjugated synthetic peptide derived from mouse FAS

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at 4°C for 12 months.

Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)

Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhou, Ke-Wen, et al. "Overexpression of CIRP may reduce testicular damage induced by cryptorchidism." Clinical & Investigative Medicine 32.2 (2009): E103-E111.Read more>>
  • Peng et al. Effects and Mechanism of Baicalin on Apoptosis of Cervical Cancer HeLa Cells I n -v itro. (2015) Iran.J.Pharm.Re. 14:251-61Read more>>
  • Wang Q et al. Cdc20 and molecular chaperone CCT2 and CCT5 are required for the Muscovy duck reovirus p10. 8-induced cell cycle arrest and apoptosis. Vet Microbiol. 2019 Jun 28;235:151-163.Read more>>