Host: Rabbit

Target Protein: HSP70 1A/1B

Immunogen Range: 500-600/641

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3303

Swiss Prot: P08107

Source: KLH conjugated synthetic peptide derived from human HSP70 1A/1B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at 4°C for 12 months.

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.