bs-0293M-HRP [Conjugated Secondary Antibody]
Mouse Anti-Rat IgG Antibody (H+L), HRP Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Clonality: Polyclonal

Isotype: IgG

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 200ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jia et al. Overexpression of indoleamine 2, 3-dioxygenase contributes to the repair of human airway epithelial cells inhibited by dexamethasone via affecting the MAPK/ERK signaling pathway. (2018) Exp.Ther.Med. 16:282-290Read more>>
  • Zhu et al. Aucubin suppresses Titanium particles‑mediated apoptosis of MC3T3‑E1 cells and facilitates osteogenesis by affecting the BMP2/Smads/RunX2 signaling pathway. (2018) Mol.Med.Rep. 18:2561-2570Read more>>
  • He and Zhu Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway. (2018) Med.Sci.Monit. 24:4982-4991Read more>>
  • Jia et al. CDMP1 overexpression mediates inflammatory cytokine‑induced apoptosis via inhibiting the Wnt/β‑Catenin pathway in rat dorsal root ganglia neurons. (2018) Int.J.Mol.Med. 42:1247-1256Read more>>
  • "Li H et al. Low‑frequency ultrasound and microbubbles combined with simvastatin promote the apoptosis of MCF‑7 cells by affecting the LATS1/YAP/RHAMM pathway H Li, C Chen, D Wang - Molecular Medicine ReportsMol Med Rep. 2018 Sep;18(3):2724-2732. "Read more>>
  • Dajing Jianget al. The protective effect of decoction of Rehmanniae via PI3K/Akt/mTOR pathway in MPP+-induced Parkinson's disease model cells. J Recept Signal Transduct Res. 2021 Feb;41(1):74-84.Read more>>
  • Xu Zhiwei. et al. Protective Effects of Interleukin-37 Expression against Acetaminophen-Induced Hepatotoxicity in Mice. EVID-BASED COMPL ALT. Evid-Based Compl Alt. 2022;2022:6468299Read more>>
  • Ze-Nan Huang. et al. Melatonin alleviates oxidative stress-induced injury to nucleus pulposus-derived mesenchymal stem cells through activating PI3K/Akt pathway. J ORTHOP TRANSL. 2023 Nov;43:66Read more>>