bs-0294M [Secondary Antibody]
Mouse Anti-Goat IgG Antibody (H+L)
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Clonality: Polyclonal

Isotype: IgG

Purification: Purified by Protein A.

Storage Buffer: Lyophilized

Storage: Store at -20°C for 12 months.

Background:

Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Size: 1mg

Concentration: Determined by end user

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Cross Reactive Species: Goat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Liu, Yaowen, et al. "Hepatocyte Cocultures with Endothelial Cells and Fibroblasts on Micropatterned Fibrous Mats to Promote Liver-specific Functions and Capillary Formation Capabilities." Biomacromolecules (2014).Read more>>
  • Liu, Yaowen, et al. "Promoting hepatocyte spheroid formation and functions by coculture with fibroblasts on micropatterned electrospun fibrous scaffolds."Journal of Materials Chemistry B (2014).Read more>>
  • Shao, Bo, et al. "Expression changes and significance of neurite outgrowth inhibitor A (Nogo-A), glial fibrillary acidic protein and insulin-like growth factor-1 in rat brain tissues after craniocerebral injury." Biomedical Research 28.1 (2017).Read more>>
  • Liu, Qian, et al. "Cyclophosphamide-induced HCN1 channel upregulation in interstitial Cajal-like cells leads to bladder hyperactivity in mice." Experimental & Molecular Medicine (2017) 49.Read more>>
  • Zhuang, Likun, et al. "MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma." Cell Death & Disease 8.5 (2017): e2804.Read more>>
  • Liu, Yaowen, Ke Hu, and Yihao Wang. "Primary Hepatocytes Cultured on a Fiber-Embedded PDMS Chip to Study Drug Metabolism." Polymers 9.6 (2017): 215.Read more>>
  • Zhou et al. Effect of kidney-reinforcing and marrow-beneficial Chinese medicine on bone metabolism-related factors following spinal cord injury in rats. (2016) Exp.Ther.Med. 12:485-491Read more>>
  • Liu et al. Decreased hyperpolarization-activated cyclic nucleotide-gated channels are involved in bladder dysfunction associated with spinal cord injury. (2018) Int.J.Mol.Med. 41:2609-2618Read more>>
  • Wang M et al. Protein 14-3-3ε Regulates Cell Proliferation and Casein Synthesis via PI3K-mTOR Pathway in Dairy Cow Mammary Epithelial Cells.(2018) J. Agric. Food Chem. Nov 14;66(45):12000-12008. Read more>>
  • Tang F et al. LncRNA‐ATB promotes TGF‐β‐induced glioma cells invasion through NF‐κB and P38/MAPK pathway. J Cell Physiol. 2019 May 29. Read more>>
  • Mu JY et al. Astragalus polysaccharide restores activation of NK cells in radiation therapy of tumors. Int J Clin Exp Med 2019;12(7):8609-8621.Read more>>
  • "B Shu et al. Cholesterol induces dedifferentiation of vascular smooth muscle cells by regulating monocyte chemotactic protein-1-induced protein 1. Int J Clin Exp Pathol 2019;12(9):3258-3267"Read more>>
  • Yuanyuan Wanget al. NLRC5 negatively regulates inflammatory responses in LPS-induced acute lung injury through NF-B and p38 MAPK signal pathways. Toxicol Appl Pharmacol. 2020 Sep 15;403:115150.Read more>>
  • Zijian Geng. et al. LPS-induced SOCS3 antagonizes the JAK2-STAT5 pathway and inhibits -casein synthesis in bovine mammary epithelial cells. Life Sci. 2021 Aug;278:119547Read more>>
  • Jinzhu Han. et al. Circ_0027599 elevates RUNX1 expression via sponging miR-21-5p on gastric cancer progression. 2021 May 25Read more>>
  • Yadi Xu. et al. DNMT1 Mediated CAHM Repression Promotes Glioma Invasion via SPAK/JNK Pathway. 2021 Jul 06Read more>>
  • Lulu Wang. et al. METTL3 is a key regulator of milk synthesis in mammary epithelial cells. 2021 Dec 11Read more>>
  • Xu Zhiwei. et al. Protective Effects of Interleukin-37 Expression against Acetaminophen-Induced Hepatotoxicity in Mice. EVID-BASED COMPL ALT. Evid-Based Compl Alt. 2022;2022:6468299Read more>>
  • Huirong Pan. et al. Goats with low levels of AAV antibody may serve as candidates for large animal gene therapy. EXP EYE RES. 2023 May;:109514Read more>>