bs-0315R [Primary Antibody]
FGL2 Polyclonal Antibody
www.biossusa.com
[email protected]
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DATASHEET

Host: Rabbit

Target Protein: FGL2

Immunogen Range: 75-150/422


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 84586

Swiss Prot: G3V7P2

Source: KLH conjugated synthetic peptide derived from rat FGL2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 49


Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yang, Siyoung, et al. "Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." Science 348.6234 (2015): 589-594.Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded: rat kidney tissue labeled with Anti-fg-12 Polyclonal Antibody (bs-0315R), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining