bs-0334R [Primary Antibody]
MTLC Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MTLC

Immunogen Range: 21-100/235


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 80177

Swiss Prot: Q8N699

Source: KLH conjugated synthetic peptide derived from human MTLC

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 27


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Li Y et al. Yin Yang Gong Ji pill is an ancient formula with antitumor activity against hepatoma cells J Ethnopharmacol. 2019 Oct 3;248:112267.Read more>>
  • "Zhang C et al. MiR-429 regulates rat liver regeneration and hepatocyte proliferation by targeting JUN/MYC/BCL2/CCND1 signaling pathway.Cell Signal. 2018 Oct;50:80-89."Read more>>
VALIDATION IMAGES

Mouse brain lysates probed with MTLC Polyclonal Antibody, unconjugated (bs-0334R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C.


Formalin-fixed and paraffin embedded: human colon carcinoma labeled with Anti-MTLC Polyclonal Antibody (bs-0334R), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining