Host: Rabbit
Target Protein: GLUT2
Immunogen Range: 431-524/524
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6514
Swiss Prot: P11168
Source: KLH conjugated synthetic peptide derived from human GLUT2
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at 4°C for 12 months.
Background: Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
Conjugation: ALEXA FLUOR® 350
Excitation/ Emission: 343nm/442nm
Size: 100ul
Concentration: 1ug/ul
Applications:
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Cross Reactive Species:
Human
Mouse
Rat
Goat
Others
Predicted Cross Reactive Species:
Dog
Cow
Sheep
Pig
Chicken
For research use only. Not intended for diagnostic or therapeutic use.
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- Zheng, Liming, et al. "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." Scientific Reports 6 (2016): 37414.Read more>>
- Guttman et al. α1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β-cells in favor of protection from autoimmune diabetes. (2014) Immunology. Read more>>
- Wang,et al.Oat globulin peptides regulate antidiabetic drug targets and glucose transporters in Caco-2 cells.(2018) Journal of Functional Foods. 42:12-20.Read more>>
- Wang N et al. Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine.(2019) Biomedicine & Pharmacotherapy, 109, 1070–1077. Read more>>
- Jiang T et al. Protein-bound Anthocyanin Compounds of Purple Sweet Potato (p-BAC-PSP) Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High Fat Diet/Streptozotocin-Induced Diabetic Mice. J Agric Food Chem. 2020 Feb 12;68(6):1596-1608.Read more>>
- "Tian C et al. Short communication: A high-grain diet entails alteration in nutrient chemosensing of the rumen epithelium in goats. Animal Feed Science and Technology. Volume 262, April 2020, 114410. "Read more>>
Hep G2 cells probed with GLUT2 Polyclonal Antibody, unconjugated (bs-0351R) at 1:100 dilution for 30 minutes compared to control cells (dark blue), secondary only (light blue) and isotype control (orange)