bs-0351R-FITC [Conjugated Primary Antibody]
GLUT2 Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GLUT2

Immunogen Range: 431-524/524


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6514

Swiss Prot: P11168

Source: KLH conjugated synthetic peptide derived from human GLUT2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 54


Cross Reactive Species: Human
Mouse
Rat
Goat
Others

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Guttman, Ofer, et al. "α1‐Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β‐cells in favor of protection from autoimmune diabetes." Immunology (2014).Read more>>
  • Zheng, Liming, et al. "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." Scientific Reports 6 (2016): 37414.Read more>>
  • Guttman et al. α1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β-cells in favor of protection from autoimmune diabetes. (2014) Immunology. Read more>>
  • Wang,et al.Oat globulin peptides regulate antidiabetic drug targets and glucose transporters in Caco-2 cells.(2018) Journal of Functional Foods. 42:12-20.Read more>>
  • Wang N et al. Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine.(2019) Biomedicine & Pharmacotherapy, 109, 1070–1077. Read more>>
  • Jiang T et al. Protein-bound Anthocyanin Compounds of Purple Sweet Potato (p-BAC-PSP) Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High Fat Diet/Streptozotocin-Induced Diabetic Mice. J Agric Food Chem. 2020 Feb 12;68(6):1596-1608.Read more>>
  • "Tian C et al. Short communication: A high-grain diet entails alteration in nutrient chemosensing of the rumen epithelium in goats. Animal Feed Science and Technology. Volume 262, April 2020, 114410. "Read more>>
  • Pengli Wang. et al. The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver. Mol Cell Endocrinol. 2020 Dec;518:111022Read more>>
  • Wang Zhe. et al. Total flavonoids of Astragalus Ameliorated Bile Acid Metabolism Dysfunction in Diabetes Mellitus. Evid-Based Compl Alt. 2021;2021:6675567Read more>>
  • Yu-Zhong Chen. et al. Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice. FRONT NUTR. 2022; 9: 854725Read more>>
  • Lihuan Zhang. et al. Effects of three probiotics and their interactions on the growth performance of and nutrient absorption in broilers. PEERJ. 2022 May;10:e13308Read more>>
  • Johan K. E. Spetz. et al. Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapyCinduced toxicities. SCI ADV. 2022 NovRead more>>
  • Yang Liu. et al. Methylation, Hydroxylation, Glycosylation and Acylation Affect the Transport of Wine Anthocyanins in Caco-2 Cells. FOODS. 2022 Jan;11(23):3793Read more>>
  • Qun Cheng. et al. Zearalenone Exposure Affects the Keap1–Nrf2 Signaling Patway and Glucose Nutrient Absorption Related Genes of Porcine Jejunal Epithelial Cells. TOXINS. 2022 Nov;14(11):793Read more>>
  • Huiqin Guo. et al. Oat -D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis. INT J BIOL MACROMOL. 2023 Jul;:126039Read more>>
  • Tianfeng Chen. et al. Islet hypoplasia of adult offspring rats caused by intrauterine chronic hypoxia is compensated by up-regulation of INS and PDX-1. ISLETS. 2023;15(1):Article: 223161Read more>>
VALIDATION IMAGES