Host: Rabbit
Target Protein: TIMP-3
Immunogen Range: 151-211/211
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 7078
Swiss Prot: P35625
Source: KLH conjugated synthetic peptide derived from human TIMP-3
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at -20°C for 12 months.
Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Conjugation: Biotin
Excitation/ Emission: N/A
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-1000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
Cross Reactive Species:
Human
Rat
Rabbit
Predicted Cross Reactive Species:
Mouse
Cow
Pig
Horse
For research use only. Not intended for diagnostic or therapeutic use.
- Liu, Wen-bin, et al. "Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a." Toxicology and applied pharmacology 251.1 (2011): 70-78.Read more>>
- Peng, Jiayin, et al. "Expression and regulative function of tissue inhibitor of metalloproteinase 3 in the goat ovary and its role in cultured granulosa cells."Molecular and Cellular Endocrinology (2015).Read more>>
- Peng, Jiayin, et al. "Expression and regulation of tissue inhibitors of metalloproteinases (TIMP1 and TIMP3) in goat oviduct." Theriogenology(2015).Read more>>
- Lu, Minling, et al. "The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage." Cells Tissues Organs 196.3 (2012): 241-250.Read more>>
- Han, Jing, et al. "Long-Term Selenium-Deficient Diet Induces Liver Damage by Altering Hepatocyte Ultrastructure and MMP1/3 and TIMP1/3 Expression in Growing Rats." Biological Trace Element Research (2016): 1-9.Read more>>