Host: Rabbit
Target Protein: DR3
Immunogen Range: 351-417/417
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8718
Swiss Prot: Q93038
Source: KLH conjugated synthetic peptide derived from human DR3
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at 4°C for 12 months.
Background: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Conjugation: ALEXA FLUOR® 555
Excitation/ Emission: 553nm/568nm
Size: 100ul
Concentration: 1ug/ul
Applications:
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Cross Reactive Species:
Human
Mouse
Rat
For research use only. Not intended for diagnostic or therapeutic use.
- Ślebioda, Tomasz Jerzy, et al. "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients."Scandinavian Journal of Immunology (2015).Read more>>
Tissue/cell:SH-SY5Y cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum,C-0005) at 37°C for 20 min; Antibody incubation with (DR3) polyclonal Antibody, Unconjugated (bs-0421R) 1:100, 90 minutes at 37°C; followed by a FITC conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.