bs-0432R-Cy7 [Conjugated Secondary Antibody]
Rabbit Anti-Chicken IgY Antibody, Cy7 Conjugated
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Host: Rabbit

Target Protein: Chicken IgY

Clonality: Polyclonal

Isotype: IgG

Source: Chicken IgY

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Background:

In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 200ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1-2)

Cross Reactive Species: Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ren, Shaoda, et al. "< i> Arnebia</i> preventing the expression of Muc1 protein decrease results in anti-implantation in early pregnant mice." Contraception 83.4 (2011): 378-384.Read more>>
  • Liu, Dong, and Zhong-Xiang Niu. "Cloning of a gene fragment encoding chicken complement component C3d with expression and immunogenicity of Newcastle disease virus F gene?CC3d fusion protein."Avian Pathology 37.5 (2008): 477-485.iRead more>>
  • Xu et al. A Critical Role of Bacterioferritin in Salmonella pullorum-Induced IFN-β Expression in DF-1 Cells. (2016) Front.Microbiol. 7:20Read more>>