bs-0446R [Primary Antibody]
FOXE1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: FOXE1

Immunogen Range: 101-200/373


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2304

Swiss Prot: O00358

Source: KLH conjugated synthetic peptide derived from human FOXE1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Probable transcription factor. Could be involved in thyroid gland organogenesis.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 41


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang, Qi, et al. "Methamphetamine induces hepatotoxicity via inhibiting cell division, arresting cell cycle and activating apoptosis: In vivo and in vitro studies." Food and Chemical Toxicology (2017).Read more>>
  • Ran Q et al. Generation of Thyroid Tissues From Embryonic Stem Cells via Blastocyst Complementation In VivoFront Endocrinol (Lausanne).2020 Dec 14;11:609697.Read more>>
  • Dong X et al. PM2.5 disrupts thyroid hormone homeostasis through activation of the hypothalamic-pituitary-thyroid (HPT) axis and induction of hepatic transthyretin in female rats 2.5Ecotoxicol Environ Saf.2021 Jan 15;208:111720.Read more>>
  • Dong, Xinwen. et al. Protective effects of curcumin against thyroid hormone imbalance after gas explosion-induced traumatic brain injury via activation of the hypothalamic-pituitary-thyroid axis in male rats. ENVIRON SCI POLLUT R. 2022 May;:1-13Read more>>
  • Lim Grace. et al. Foxe1 Deletion in the Adult Mouse is Associated with Increased Thyroidal Mast Cells and Hypothyroidism. ENDOCRINOLOGY. 2022 SepRead more>>
VALIDATION IMAGES

Lane 1: mouse brain lysates Lane 2: mouse thyroid lysates probed with Anti TTF-2/FOXE1 Polyclonal Antibody, Unconjugated (bs-0446R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted band 41kD. Observed band size: 41kD.


Mouse kidney lysates probed with FOXE1 Polyclonal Antibody, Unconjugated (bs-0446R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.