bs-0460R [Primary Antibody]
TSHR Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: TSHR

Immunogen Range: 501-600/764

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7253

Swiss Prot: P16473

Source: KLH conjugated synthetic peptide derived from human TSHR

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage: Store at -20°C for 12 months..

Background:

Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).

Size: 100ul

Concentration: 1ug/ul

Predicted Molecular Weight: 86

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Sheep
Pig
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang ML et al. MALAT1 rs619586 polymorphism functions as a prognostic biomarker in the management of differentiated thyroid carcinoma. J Cell Physiol. 2019 Aug 27. Read more>>
  • Dong X et al. PM2.5 disrupts thyroid hormone homeostasis through activation of the hypothalamic-pituitary-thyroid (HPT) axis and induction of hepatic transthyretin in female rats 2.5Ecotoxicol Environ Saf.2021 Jan 15;208:111720.Read more>>
VALIDATION IMAGES

Mouse thymocytes probed with Rabbit Anti-TSHR Polyclonal Antibody, Unconjugated (bs-0460R) (green) at 1:100 for 60 minutes followed by a FITC conjugated secondary compared to control cells (blue).


Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti-TSHR Polyclonal Antibody (bs-0460R)at 1:200 followed by conjugation to the secondary antibody and DAB staining