Host: Rabbit
Target Protein: CD45
Specificity: The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.
Immunogen Range: 1210-1304/1304
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5788
Swiss Prot: P08575
Source: KLH conjugated synthetic peptide derived from human CD45
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at -20°C for 12 months.
Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Conjugation: Biotin
Excitation/ Emission: N/A
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-1000)
ELISA(1:500-1000)
Cross Reactive Species:
Human
Mouse
Rabbit
Predicted Cross Reactive Species:
Rat
Cow
For research use only. Not intended for diagnostic or therapeutic use.
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