bs-0600R-A350 [Conjugated Primary Antibody]
ADRA1A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: ADRA1A

Immunogen Range: 201-300/466


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 148

Swiss Prot: P35348

Source: KLH conjugated synthetic peptide derived from human Alpha-1A adrenergic receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 51


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig
Horse
Chicken
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Sun, Tao, et al. "Antihypertensive effect of formononetin through regulating the expressions of eNOS, 5-HT< sub> 2A/1B</sub> receptors and α< sub> 1</sub>-adrenoceptors in spontaneously hypertensive rat arteries." European Journal of Pharmacology (2013).Read more>>
  • Chen, Li-You, et al. "Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency." Brain Structure and Function (2014): 1-14.Read more>>
  • Wang, Wenjuan, et al. "Effects of Estradiol Valerate and Remifemin on Norepinephrine Signaling in the Brain of Ovariectomized Rats."Neuroendocrinology 101.2 (2015): 120-132.Read more>>
  • Jianchao Ren. et al. Ejaculatory Duct Obstruction Affects Seminal Vesicle Contractile Efficacy and Smooth Muscle Ultrastructure in a Rat Model. ANDROLOGIA. 2023;2023:5022466Read more>>
VALIDATION IMAGES