bs-0634R-Biotin [Conjugated Primary Antibody]
Aquaporin 4 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Aquaporin 4

Immunogen Range: 271-323/323


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 11829

Swiss Prot: P55088

Source: KLH conjugated synthetic peptide derived from mouse AQP4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 36


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Sheep
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Gang, Zhang, et al. "Detection of hypoxic-ischemic brain injury with 3D-enhanced T2* weighted angiography (ESWAN) imaging." European Journal of Radiology (2013).Read more>>
  • Duan, Hubin, et al. "The role of neuropeptide Y and aquaporin 4 in the pathogenesis of intestinal dysfunction caused by traumatic brain injury." Journal of Surgical Research (2013).Read more>>
  • Li, Cheng, et al. "Melatonin lowers edema after spinal cord injury." Neural Regeneration Research 9.24 (2014): 2205.Read more>>
  • Rajesh, Kumar, Li Xiaojie, and Kong Xiangying. "The Effect of Early Intervention and Rehabilitation in the Expression of Aquaporin-4; and Ultrastructure Changes on Rats Offsprings Damaged Brain Caused by Intrauterine Infection." Journal of Korean Neurosurgical Society 58.1 (2015): 14-21.Read more>>
  • Cao et al. Hypertonic saline reduces lipopolysaccharide-induced mouse brain edema through inhibiting aquaporin 4 expression. (2012) Crit.Care. 16:R186Read more>>
  • Takanori Watanabe et al. Aquaporin 3 Expression in Endometrioid Carcinoma of the Uterine Body Correlated With Early Stage and Lower Grade. Pathol Oncol Res. 2020 Oct;26(4):2247-2253.Read more>>
  • Luis Alfonso Gonzlez-Molina. et al. Extracellular Vesicles From 3xTg-AD Mouse and Alzheimers Disease Patient Astrocytes Impair Neuroglial and Vascular Components. Front Aging Neurosci. 2021; 13: 593927Read more>>
  • Juan Villar-Vesga. et al. Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimers Disease Leads to Neuroglial and Endothelial Cell Degeneration. Front Aging Neurosci. 2020; 12: 587989Read more>>
  • Ganggang Li. et al. Baicalin suppresses neuron autophagy and apoptosis by regulating astrocyte polarization in pentylenetetrazol-induced epileptic rats and PC12 cells. Brain Res. 2022 Jan;1774:147723Read more>>
  • Clark, Iain C.. et al. Identification of astrocyte regulators by nucleic acid cytometry. NATURE. 2023 Jan;:1-3Read more>>
  • Huijun LI. et al. Screening the effective components in treating dampness stagnancy due to spleen deficiency syndrome and elucidating the potential mechanism of Poria water extract. CHIN J NAT MEDICINES. 2023 Feb;21:83Read more>>
  • Yimeng Fan. et al. Pingwei San Ameliorates Spleen Deficiency-Induced Diarrhea through Intestinal Barrier Protection and Gut Microbiota Modulation. ANTIOXIDANTS-BASEL. 2023 May;12(5):1122Read more>>
VALIDATION IMAGES