bs-0651R [Primary Antibody]
Connexin 43 Polyclonal Antibody
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]

Host: Rabbit

Target Protein: Connexin 43

Immunogen Range: 211-260/382

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2697

Swiss Prot: P17302

Source: KLH conjugated synthetic peptide derived from human Connexin-43

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage: Store at -20°C for 12 months.

Background: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)

Predicted Molecular Weight: 42

Cross Reactive Species: Human

Predicted Cross Reactive Species: Cow

For research use only. Not intended for diagnostic or therapeutic use.

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  • Chen et al. Carbenoxolone pretreatment and treatment of posttraumatic epilepsy. (2013) Neural.Regen.Res. 8:169-76Read more>>
  • Zhan C et al. Rotenone and 3-bromopyruvate toxicity impacts electrical and structural cardiac remodeling in rats. Toxicol Lett. 2019 Oct 1. pii: S0378-4274(19)30295-4. Read more>>
  • Inayatilah F et al. Monoclonal antibodies of human zona pellucida 3 (MabhZP3) as immunocontraception candidate on connexin expression 43 (Cx43) in granulosa ovarian cell and luteinizing hormone level in the blood serum of mice (Mus musculus). Drug Invention Today.12 (11)2019.Read more>>
  • Hui Li. et al. Curcumin Alleviates the Side Effects of Cisplatin on Gastric Emptying of Mice by Inhibiting the Signal Changes of Acetylcholine and Interstitial Cells of Cajal. J Med Food. 2020 Sep;23(9):920-927Read more>>
  • Peng Lin. et al. Curcumin relieves mice gastric emptying dysfunction induced by L?arginine and atropine through interstitial cells of Cajal. Exp Ther Med. 2021 Jun;21(6):1-6Read more>>

Formalin-fixed and paraffin embedded rat heart tissue labeled Anti-Connexin 43 Polyclonal Antibody, Unconjugated (bs-0651R) at 1:200, followed by conjugation to the secondary antibody and DAB staining