bs-0705R-FITC [Conjugated Primary Antibody]
LDL receptor Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: LDL receptor

Immunogen Range: 781-860/860


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3949

Swiss Prot: P01130

Source: KLH conjugated synthetic peptide derived from human LDL-R

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 92


Cross Reactive Species: Human
Mouse
Rat
Plant
Hamster
(Hamster)

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wu, Hao, et al. "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." Phytomedicine (2014).Read more>>
  • Kou, Shuming, et al. "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." Life Sciences (2016).Read more>>
  • Jia, Lianqun., et al. "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." Molecular Medicine Reports (2016).Read more>>
  • Saxena et al. Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System. (2018) Asian.Pac.J.Cancer.Prev. 19:81-90Read more>>
  • Grube,et al.Mining the Secretome of C2C12 Muscle Cells: Data Dependent Experimental Approach To Analyze Protein Secretion Using Label-Free Quantification and Peptide Based Analysis.(2018) Journal of Proteome Research. 17:879-890.Read more>>
  • Kwon,et al.Luterion and separating and culturing methods for same.(2017) . Read more>>
  • Kaur AP et al. Differential response of T cells to an immunogen, a mitogen and a chemical carcinogen in a mouse model system. J Biochem Mol Toxicol. 2019 May;33(5):e22290. Read more>>
  • Kyoung Jin Leeet al. Real-time monitoring of oncolytic VSV properties in a novel in vitro microphysiological system containing 3D multicellular tumor spheroids. PLoS One. 2020 Jul 6;15(7):e0235356.Read more>>
  • Wei Zou. et al. Imperatae rhizoma-Hedyotis diffusa Willd. herbal pair alleviates nephrotic syndrome by integrating anti-inflammatory and hypolipidaemic effects. Phytomedicine. 2021 Sep;90:153644Read more>>
  • Mei Hui. et al. The Hypolipidemic Effect of Dalbergia odorifera T. C. Chen Leaf Extract on Hyperlipidemic Rats and Its Mechanism Investigation Based on Network Pharmacology. Evid-Based Compl Alt. 2021;2021:3155266Read more>>
  • Huiming Hu. et al. The Hypolipidemic Effect of Hawthorn Leaf Flavonoids through Modulating Lipid Metabolism and Gut Microbiota in Hyperlipidemic Rats.. EVID-BASED COMPL ALT. 2022 Nov;2022:3033311-3033311Read more>>
  • Shuzhou Wang. et al. Effects of NAC assisted insulin on cholesterol metabolism disorders in canine type 1 diabetes mellitus. LIFE SCI. 2022 Dec;:121193Read more>>
VALIDATION IMAGES