Host: Rabbit
Target Protein: CTGF
Immunogen Range: 221-349/349
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1490
Swiss Prot: P29279
Source: KLH conjugated synthetic peptide derived from human CTGF
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at 4°C for 12 months.
Background: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Conjugation: FITC
Excitation/ Emission: 494nm/518nm
Size: 100ul
Concentration: 1ug/ul
Applications:
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Cross Reactive Species:
Human
Mouse
Rat
Predicted Cross Reactive Species:
Dog
Cow
Pig
Chicken
For research use only. Not intended for diagnostic or therapeutic use.
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- Ciamporcero, E., et al. "YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage." Oncogene (2015).Read more>>
- Al-hamilly, Nadia Saeed, et al. "Biological roles of KGF, CTGF and TGF-β in cyclosporine-A-and phenytoin-induced gingival overgrowth: A comparative experimental animal study." Archives of oral biology 66 (2016): 38-43.Read more>>
- Gendron, David R., et al. "FTY720 promotes pulmonary fibrosis when administered during the remodelling phase following a bleomycin-induced lung injury." Pulmonary Pharmacology & Therapeutics (2017).Read more>>
- He, Hongying, et al. "Carbamylated erythropoietin ameliorates cardiomyopathy via ERK (44/42) activation in rats with diabetic cardiomyopathy." Int J Clin Exp Med 10.10 (2017): 14213-14222.Read more>>
- Han et al. MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma. (2016) Med.Sci.Moni. 22:3925-3934Read more>>
- Guo et al. High-salt intake suppressed microRNA-133a expression in Dahl SS rat myocardium. (2014) Int.J.Mol.Sc. 15:10794-805Read more>>
- Ciamporcero et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. (2016) Oncogene. 35:1541-53Read more>>
- Zhang et al. Apelin-13 protects against myocardial infarction-induced myocardial fibrosis. (2016) Mol.Med.Rep. 13:5262-8Read more>>
- Chi et al. Transdermal estrogen gel and oral aspirin combination therapy improves fertility prognosis via the promotion of endometrial receptivity in moderate to severe intrauterine adhesion. (2018) Mol.Med.Rep. 17:6337-6344Read more>>