bs-0780R [Primary Antibody]
IL-8 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IL-8

Immunogen Range: 31-99/99

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3576

Swiss Prot: P10145

Source: KLH conjugated synthetic peptide derived from human IL-8

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at -20°C for 12 months..

Background: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-1-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat
Rabbit

Predicted Cross Reactive Species: Cow
Sheep
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ma, Yanqin, et al. "Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta." Archives of toxicology 86.6 (2012): 849-856.Read more>>
  • Lu, Yongping, et al. "Assessment of atherosclerotic plaques in the rabbit abdominal aorta with interleukin-8 monoclonal antibody-targeted ultrasound microbubbles." Molecular biology reports (2013): 1-10.Read more>>
  • Zhang, Tao, et al. "CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment." Nature Communications 7 (2016).Read more>>
  • Huang, Qi. "IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma." Scientific Reports 6 (2016).Read more>>
  • Xu et al. Extracts of Bauhinia championii (Benth.) Benth. attenuate the inflammatory response in a rat model of collagen-induced arthritis. (2016) Mol.Med.Re. 13:4167-74Read more>>
  • Ding S et al. Inflammatory cytokines tumor necrosis factor-α and interleukin-8 enhance airway smooth muscle contraction by increasing L-type Ca channel expression.(2018) Clin. Exp. Pharmacol. Physiol.Sep 10Read more>>
  • Verma S et al. Non-invasive oral cancer detection from saliva using zinc oxide–reduced graphene oxide nanocomposite based bioelectrode. MRS Communications,2019, 1–8. Read more>>
  • Yang W et al. The Effect of Low and High Dose Deoxynivalenol on Intestinal Morphology, Distribution, and Expression of Inflammatory Cytokines of Weaning Rabbits. Toxins (Basel). 2019 Aug 13;11(8). pii: E473.Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rabbit carotid artery labeled with Anti-IL-8/CXCL8 Polyclonal Antibody, Unconjugated (bs-0780R) at 1:200, followed by conjugation to the secondary antibody and DAB staining