bs-0961R-A488 [Conjugated Primary Antibody]
Leptin receptor Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Leptin receptor

Immunogen Range: 501-600/1165


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3953

Swiss Prot: P48357

Source: KLH conjugated synthetic peptide derived from human of human Leptin receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 490nm/525nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 130


Cross Reactive Species: Human
Mouse
Rat
Others

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • De Matteis, Giovanna, et al. "Evaluation of Leptin receptor expression on buffalo leukocytes." Veterinary Immunology and Immunopathology (2016).Read more>>
  • Zhang W et al. Neuroprotective effects of leptin on cerebral ischemia through JAK2/STAT3/PGC-1-mediated mitochondrial function modulation. Brain Res Bull. 2020 Mar;156:118-130. Read more>>
  • Yuri Nambu. et al. Effects of leptin on proliferation of astrocyte- and tanycyte-like neural stem cells in the adult mouse medulla oblongata. Neurosci Res. 2021 MayRead more>>
  • Shengyan Xi. et al. The Ciji-Huaai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H22 Hepatocellular Carcinoma. Front Pharmacol. 2021; 12: 715824Read more>>
  • Wang Shan. et al. DAPK1 Interacts with the p38 isoform MAPK14, Preventing its Nuclear Translocation and Stimulation of Bone Marrow Adipogenesis. Stem Cells. 2022 FebRead more>>
  • Yan Zhuang. et al. A novel leptin receptor binding peptide tethered-collagen scaffold promotes lung injury repair. BIOMATERIALS. 2022 Nov;:121884Read more>>
VALIDATION IMAGES