Host: Rabbit
Target Protein: MTNR1B
Immunogen Range: 201-300/362
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4544
Swiss Prot: P49286
Source: KLH conjugated synthetic peptide derived from human MTNR1B
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Conjugation: ALEXA FLUOR® 594
Excitation/ Emission: 590nm/617nm
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 40
Cross Reactive Species:
Human
Mouse
Rat
Goat
Predicted Cross Reactive Species: Dog
For research use only. Not intended for diagnostic or therapeutic use.
- Wang, S-J., et al. "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." Theriogenology 78.7 (2012): 1517-1526.Read more>>
- Brockus, K. E., et al. "Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers." Domestic Animal Endocrinology (2015).Read more>>
- Jang, Hoon, et al. "Synergistic effect of melatonin and ghrelin in preventing cisplatin‐induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles." Journal of Pineal Research (2017).Read more>>
- Zhang W et al. The inhibitory effect of melatonin on mammary function of lactating dairy goats.(2018) Biol Reprod. Oct 22.Read more>>
- Gao Y et al. Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells.Cell Mol Biol Lett. 2019 Mar 12;24:21.Read more>>
- Zhao Shu-Qin. et al. The in vitro effects of melatonin and Cry gene on the secretion of estradiol from camel ovarian granulosa cells. Domest Anim Endocrin. 2021 Jan;74:106497Read more>>
- S-Q. Zhao. et al. cAMP/PKA/CREB signaling pathway-mediated effects of melatonin receptor genes on clock gene expression in Bactrian camel ovarian granulosa cells. Domest Anim Endocrin. 2021 Jul;76:106609Read more>>
- Donghui Yang. et al. Melatonin alleviates LPS\induced endoplasmic reticulum stress and inflammation in spermatogonial stem cells. J Cell Physiol. 2021 May;236(5):3536-3551Read more>>
- Shanshan Yu. et al. Melatonin prevents experimental central serous chorioretinopathy in rats. J PINEAL RES. 2022 Apr 29Read more>>
- Jie Yang. et al. Exposure to Benzo(a)pyrene damages mitochondrial function via suppressing mitochondrial melatonin receptors in ovarian corpus luteum during early pregnancy. CHEM-BIOL INTERACT. 2022 Aug;:110085Read more>>
- Wenbo Ge. et al. Melatonin protects sheep endometrial epithelial cells against lipopolysaccharide-induced inflammation in vitro. REPROD DOMEST ANIM. 2022 AugRead more>>
- Hongwei Duan. et al. Melatonin regulates dihydrotestosterone formation via its membrane receptor in the epididymal epithelial cells of sheep. THERIOGENOLOGY. 2022 DecRead more>>
- Junyuan Ma. et al. Effects of melatonin on development and hormone secretion of sheep theca cells in?vitro. THERIOGENOLOGY. 2023 Mar;198:172Read more>>
- Gao Xinran. et al. Role of Bmal1 in Type 2 Diabetes Mellitus-Related Glycolipid Metabolic Disorder and Neuropsychiatric Injury: Involved in the Regulation of Synaptic Plasticity and Circadian Rhythms. MOL NEUROBIOL. 2023 May;:1-23Read more>>
- Yunxian Dong. et al. Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling. BBA-MOL BASIS DIS. 2024 Jan;1870:166887Read more>>
- Hongwei Duan. et al. Melatonin promotes progesterone secretion in sheep luteal cells by regulating autophagy via the AMPK/mTOR pathway. THERIOGENOLOGY. 2023 NovRead more>>