bs-1007R [Primary Antibody]
DRD1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: DRD1

Immunogen Range: 101-200/446


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1812

Swiss Prot: P21728

Source: KLH conjugated synthetic peptide derived from human DRD1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 50


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • ai L et al. m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite.Toxicol Sci. 2018 Oct 1;165(2):431-446.Read more>>
  • Salgado, R., et al. "Perfluorooctane sulfonate (PFOS) exposure could modify the dopaminergic system in several limbic brain regions." Toxicology Letters(2015).Read more>>
  • Zhang, Q. B., et al. "Moderate swimming suppressed the growth and metastasis of the transplanted liver cancer in mice model: with reference to nervous system." Oncogene (2016).Read more>>
  • Yang K et al. Synaptic dopamine release is positively regulated by SNAP-25 that involves in benzo [a] pyrene-induced neurotoxicity. Chemosphere. 2019 Jul 15;237:124378. Read more>>
  • Bai L et al. m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite.Toxicol Sci. 2018 Oct 1;165(2):431-446.Read more>>
  • Li Y et al. Study on the Anticancer Effect of an Astragaloside- and Chlorogenic Acid-Containing Herbal Medicine (RLT-03) in Breast Cancer. Evid Based Complement Alternat Med. 2020 Jun 10;2020:1515081.Read more>>
  • Li Yanchu. et al. Effects of a Chlorogenic Acid-Containing Herbal Medicine (LASNB) on Colon Cancer. Evid-Based Compl Alt. 2021;2021:9923467Read more>>
  • Fiona Limanaqi. et al. Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons. CELLS-BASEL. 2022 Jan;11(10):1691Read more>>
VALIDATION IMAGES

Human 293T cells probed with DRD1 Polyclonal Antibody, unconjugated (bs-1007R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C.


Mouse cerebrum lysates probed with DRD1 Polyclonal Antibody, unconjugated (bs-1007R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C.


Mouse olfactory bulb lysates probed with DRD1 Polyclonal Antibody, Unconjugated (bs-1007R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: Mouse Cerebrum lysates; Lane 2: Rat Cerebrum lysates probed with DRD1 Polyclonal Antibody, Unconjugated (bs-1007R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: Mouse Olfactory bulb lysates; Lane 2: Rat Olfactory bulb lysates; Lane 3: Mouse Cerebrum lysates; Lane 4: Rat Cerebrum lysates; Lane 5: Rat Kidney lysates probed with DRD1 Polyclonal Antibody, Unconjugated (bs-1007R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C