Target Protein: LXR alpha + LXR beta
Immunogen Range: 410-440/447
Entrez Gene: 10062, 7376
Source: KLH conjugated synthetic peptide derived from human LXR alpha
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Background: The LXR receptors (including LXR-_ and LXR-_) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR)-activated macrophages.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.