bs-10394R [Primary Antibody]
NeuN Polyclonal Antibody
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Host: Rabbit

Target Protein: NeuN

Immunogen Range: 125-175/312


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 146713

Swiss Prot: A6NFN3

Source: KLH conjugated synthetic peptide derived from human FOX3

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

Size: 100µL

Concentration: 1ug/ul

Applications: IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Flow-Cyt(1ug/test)
ICC/IF(1:50-100)

Predicted Molecular Weight: 34 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Haoqiang Zhang. et al. Liraglutide improved the cognitive function of diabetic mice via the receptor of advanced glycation end products down-regulation.. Aging-Us. 2021 Jan 15; 13(1): 525C536Read more>>
  • Yanjing Zhu. et al. Deep learning-based predictive identification of neural stem cell differentiation. Nat Commun. 2021 May;12(1):1-13Read more>>
  • Hongmei Zhou. et al. Downregulation of beclin 1 restores arsenite-induced impaired autophagic flux by improving the lysosomal function in the brain. Ecotox Environ Safe. 2022 Jan;229:113066Read more>>
  • Danyang Li. et al. Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice. NEUROTOXICOLOGY. 2022 OcRead more>>
  • Jia Wang. et al. FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice. INT J MOL SCI. 2022 Jan;23(23):14979Read more>>
  • Chunyan Lei. et al. HMGB1/TLR4 axis promotes pyroptosis after ICH by activating the NLRP3 inflammasome. J NEUROIMMUNOL. 2024 Aug;393:578401Read more>>
VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with NeuN Polyclonal Antibody, Unconjugated (bs-10394R) at 1:200 overnight at 4°C, DAB staining.