bs-10489R-A680

DATASHEET

Host: Rabbit

Target Protein: HHV DNA polymerase catalytic subunit

Specificity: This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit

Immunogen Range: 1131-1235/1235

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.

Conjugation: ALEXA FLUOR® 680

Excitation/ Emission: 679nm/702nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 136

Cross Reactive Species: Virus
(HHV1)

For research use only. Not intended for diagnostic or therapeutic use.