bs-10498R [Primary Antibody]
CD3E Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD3E

Immunogen Range: 11-100/196


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 397455

Swiss Prot: Q7YRN2

Source: KLH conjugated synthetic peptide derived from pig CD3E

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 20


Cross Reactive Species: Human
Mouse
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Takeuchi, Hiroki, et al. "Temporal Changes in Cellular Repopulation and Collagen Fibril Remodeling and Regeneration After Allograft Anterior Cruciate Ligament Reconstruction An Experimental Study Using Kusabira-Orange Transgenic Pigs." The American Journal of Sports Medicine (2016): 0363546516650881.Read more>>
  • Zhang et al. Pathophysiology of chronic pancreatitis induced by dibutyltin dichloride joint ethanol in mice. (2016) World.J.Gastroentero. 22:2960-70Read more>>
  • Sun J et al. Clinical effects of lentinan combined with budesonide inhalation in treating acute exacerbation of chronic obstructive pulmonary disease under mechanical ventilation. Exp Ther Med. 2019 Mar;17(3):1503-1508. Read more>>
  • Pan Y et al. Amino-Modified Polymer Nanoparticles as Adjuvants to Activate the Complement System and to Improve Vaccine Efficacy in Vivo. Biomacromolecules. 2019 Sep 9;20(9):3575-3583.Read more>>
  • Xiaoshuang Zuo. et al. Photobiomodulation and diffusing optical fiber on spinal cords impact on nerve cells from normal spinal cord tissue in piglets. 2021 Jan 02Read more>>
  • Xiao-Fan Xu. et al. Aspirin Ameliorates Pancreatic Inflammation and Fibrosis by Inhibiting COX-2 Expression in Experimental Chronic Pancreatitis. J INFLAMM RES. 2022 Aug;15:4737-4749Read more>>
  • Sun, Xinxin. et al. 0.1% Nano-silver mediates PD-1/PD-L1 pathway and alleviates chronic apical periodontitis in rats. ODONTOLOGY. 2022 Sep;:1-11Read more>>
  • Qihang Hou. et al. Dietary genistein increases microbiota-derived short chain fatty acid levels, modulates homeostasis of the aging gut, and extends healthspan and lifespan. PHARMACOL RES. 2023 Feb;188:106676Read more>>
  • Ke Minhui. et al. Establishment and study of a rat internal haemorrhoid model. SCI REP-UK. 2023 Dec;13(1):1-1Read more>>