bs-10618R-Cy3 [Conjugated Primary Antibody]
Vitamin D3 Receptor Polyclonal Antibody , Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Vitamin D3 Receptor

Immunogen Range: 51-150/427


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7421

Swiss Prot: P11473

Source: KLH conjugated synthetic peptide derived from human Vitamin D3 Receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 47


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Dog
Cow
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Guo Y et al. Calcitriol attenuates renal tubular?epithelial?cells apoptosis via inhibiting p38MAPK signaling in diabetic nephropathy. Acta Diabetol. 2020 Nov;57(11):1327-1335.Read more>>
  • Juanjuan Li. et al. The effect of 1,25-dihydroxyvitamin D3 on the Wnt signaling pathway in bovine intestinal epithelial cells is mediated by the DKK2 (dickkopf2) Wnt antagonist. J STEROID BIOCHEM. 2023 Jul;231:106319Read more>>
  • Wenjing Lu. et al. Seasonal changes of vitamin D3 and ovarian steroidogenesis in the wild ground squirrels (Citellus dauricus Brandt). J STEROID BIOCHEM. 2023 Nov;234:106385Read more>>
  • Wenjing Lu. et al. Vitamin D status alters genes involved in ovarian steroidogenesis in muskrat granulosa cells. BBA-MOL CELL BIOL L. 2024 May;1869:159469Read more>>
  • ?ab?d? Natalia. et al. Dual effect of vitamin D3 on breast cancer-associated fibroblasts. BMC CANCER. 2024 Dec;24(1):1-25Read more>>