bs-1109R [Primary Antibody]
IQGAP1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IQGAP1

Immunogen Range: 1451-1550/1657


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8826

Swiss Prot: P46940

Source: KLH conjugated synthetic peptide derived from human IQGAP1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(IHC-P)(1:100-500)
IF(IHC-F)(1:100-500)
IF(ICC)(1:100-500)

Predicted Molecular Weight: 189


Cross Reactive Species: Human
Rat
Rabbit

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Sheen YS et al. Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1‐mediated increase in vascular permeability. J Pathol. 2020 Feb 7. Read more>>
  • Sheen YS et al. Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1‐mediated increase in vascular permeability. J Pathol. 2020 Feb 7. Read more>>
VALIDATION IMAGES

Formalin-fixed and rat lung tissue labeled with Anti-IQGAP1 Polyclonal Antibody, Unconjugated (bs-1109R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and rabbit placenta tissue labeled with Anti-IQGAP1 Polyclonal Antibody, Unconjugated (bs-1109R) at 1:200 followed by conjugation to the secondary antibody and DAB staining