bs-11127R [Primary Antibody]
CD11b/c Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD11b/c

Specificity: The immunogen for this product has partial sequence similarity to CD11d in mouse and rat.

Immunogen Range: 131-230/1152


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3684

Swiss Prot: P11215

Source: KLH conjugated synthetic peptide derived from human CD11b

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
FCM(1:20-100)

Predicted Molecular Weight: 125


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Riyadi PH et al. Effects of dichloromethane Sarcophyton spp. extract on the lipopolysaccharide-induced expression of nuclear factor-kappa B and inducible nitric oxide synthase in … Veterinary World, 2019,12(12): 1897-1902.Read more>>
  • orgonetti, Vittoria. et al. Posttranscriptional Regulation of Gene Expression Participates in the Myelin Restoration in Mouse Models of Multiple Sclerosis: Antisense Modulation of HuR and HuD ELAV RNA Binding Protein. MOL NEUROBIOL. 2023 Jan;:1-17Read more>>
VALIDATION IMAGES

U937 cells probed with Rabbit Anti-CD11b/c equivalent Polyclonal Antibody, A488 Conjugated (bs-11127R-A488) at 1:100 for 40 minutes at room temperature.


U937 cells probed with Rabbit Anti-CD11b/c equivalent Polyclonal Antibody,(bs-11127R) at 1:100 for 40 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Secondary Antibody, FITC Conjugated.