bs-1128R-A350 [Conjugated Primary Antibody]
SGLT1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SGLT1

Immunogen Range: 401-500/665


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 20537

Swiss Prot: Q8C3K6

Source: KLH conjugated synthetic peptide derived from mouse SGLT1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 73


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chen, Zhaolin, et al. "Efficiency of transcellular transport and efflux of flavonoids with different glycosidic units from flavonoids of< i> Litsea coreana L</i> in a MDCK epithelial cell monolayer model." European Journal of Pharmaceutical Sciences (2013).Read more>>
  • Reyer, Henry, et al. "Possible molecular mechanisms by which an essential oil blend from star anise, rosemary, thyme, and oregano and saponins increase the performance and ileal protein digestibility of growing broilers." Journal of Agricultural and Food Chemistry (2017).Read more>>
  • Wang N et al. Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine.(2019) Biomedicine & Pharmacotherapy, 109, 1070–1077. Read more>>
  • Kelly, Jennifer. et al. Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease. SCI REP-UK. 2022 Apr;12(1):1-17Read more>>
  • Gai-feng Hu. et al. SGLT1/2 as the potential biomarkers of renal damage under Apoe?/? and chronic stress via the BP neural network model and support vector machine. FRONT CARDIOVASC MED. 2022; 9: 948909Read more>>
  • Yang Liu. et al. Methylation, Hydroxylation, Glycosylation and Acylation Affect the Transport of Wine Anthocyanins in Caco-2 Cells. FOODS. 2022 Jan;11(23):3793Read more>>
  • Qun Cheng. et al. Zearalenone Exposure Affects the Keap1&ndash;Nrf2 Signaling Patway and Glucose Nutrient Absorption Related Genes of Porcine Jejunal Epithelial Cells. TOXINS. 2022 Nov;14(11):793Read more>>
  • Yaoyao Liu. et al. Cinnamon free phenolic extract regulates glucose absorption in intestinal cells by inhibiting glucose transporters. FOOD BIOSCI. 2023 Apr;52:102405Read more>>
  • Jianyi Li. et al. Adrenal SGLT1 or SGLT2 as predictors of atherosclerosis under chronic stress based on a computer algorithm. PEERJ. 2023 Aug;11:e15647Read more>>
  • Zhou Xihong. et al. Colonic phosphocholine is correlated with Candida tropicalis and promotes diarrhea and pathogen clearance. NPJ BIOFILMS MICROBI. 2023 Sep;9(1):1-13Read more>>
  • Lei Liu. et al. Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment. ACS NANO. 2024;XXXX(XXX):XXX-XXXRead more>>
  • Lu Dalu. et al. Maternal docosahexaenoic acid supplementation during lactation improves exercise performance, enhances intestinal glucose absorption and modulates gut microbiota in weaning offspring mice. FRONT NUTR. 2024 Jul;11Read more>>
VALIDATION IMAGES