bs-11470R-Biotin

DATASHEET

Host: Rabbit

Target Protein: Plexin B3

Immunogen Range: 354-400/1909

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5365

Swiss Prot: Q9ULL4

Source: KLH conjugated synthetic peptide derived from human Plexin B2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 202

Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Dog
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.